Learn about treatment

Lupron Depot^® belongs to a class of drugs called gonadotropin-releasing hormone agonists (GnRHa). Lupron Depot is the number-one prescribed* drug in its class, and has been used to manage endometriosis for more than a decade.

You can learn more about treatment in our About Lupron Depot section. Here, you will find detailed information such as how Lupron Depot works, what to expect during and after therapy, and the facts about being proactive to manage potential side effects with a supplement option known as add-back therapy.

Deciding whether Lupron Depot is an appropriate therapy for you is a decision that needs to be made together with your doctor. Our Talking to Your Doctor section is designed to give you the understanding you need before your visit. You will find information on how endometriosis is diagnosed by your doctor and a personalized Doctor Discussion Guide to help prepare you for your doctor visit. And, if you don’t currently have a doctor, we can direct you to resources that can help you find one.

* Based on IMS Health, DDD™ and NDC Health, NDC Non-Retail™, February 2004 for the U.S. market. IMS Health, DDD™ and NDC Health, NDC Non-Retail™ are not trademarks of TAP Pharmaceutical Products Inc.
Please see below for important information on Lupron Depot^®, including side effects.

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Don't ignore your chronic pelvic pain—talk to your doctor about it. Our personalized Doctor Discussion Guide offers a list of questions you can print and take with you to your next doctor visit.

Be prepared to partner with your doctor. Keep an ongoing record of your monthly symptoms in our interactive Pain Diary, and share the printouts with your doctor at each visit.

Important Safety and Other Information:

Lupron Depot^® is indicated for management of endometriosis, including pain relief and reduction of endometriotic lesions. Lupron Depot with norethindrone acetate 5 mg daily is also indicated for initial management of endometriosis and for management of recurrence of symptoms. Duration of initial treatment or retreatment should be limited to 6 months.

Most common side effects with Lupron Depot are generally those related to low estrogen levels, including hot flashes, headaches, and vaginal dryness. A small amount of bone loss (average 3.2% at month 6) may also occur during therapy with Lupron Depot alone.

The most commonly reported side effects of Lupron Depot plus norethindrone acetate 5 mg daily are hot flashes, headache, nausea/vomiting, depression/emotional liability, and asthenia. In addition, Lupron Depot plus norethindrone acetate-treated patients had significantly decreased HDL levels and significantly increased LDL/HDL rations. After treatment, mean serum lipid levels in patients with follow-up data returned to pretreatment values. Norethindrone acetate should be used with caution in women with cardiovascular risk factors including lipid abnormalities and cigarette smoking. Please refer to the norethindrone acetate prescribing information for warnings, precautions, contraindications, and adverse reactions.

Please see Complete Prescribing Information, as well as the Patient Product Information for Lupron Depot.

Visit www.lupron.com