I Am Taking Lupron Depot

Whether you are just beginning treatment or near the end of your Lupron Depot^® therapy, finding all the information and support you need is important. To encourage and enhance your learning experience, we have designed helpful interactive tools.

In our personal tools section, you will find a Pain Diary to help you keep an accurate record of your pain and symptoms as well as an Appointment Reminder to help you remember your doctor visits. You can also sign up for the ScriptAssist program, created specifically for patients on Lupron Depot, which offers free personalized over-the-telephone registered nurse support during your treatment.

If you would like more information about Lupron Depot, including how it works, what to expect during and after therapy, and the facts about taking Lupron Depot with a supplement known as add-back therapy, you will find it in our About Lupron Depot section.

Please see below for important information on Lupron Depot^®, including side effects.

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Keeping therapeutic levels of Lupron Depot in your system is important. Never miss a doctor appointment with our email Appointment Reminder.

Be prepared to partner with your doctor. Keep an ongoing record of your monthly symptoms in our interactive Pain Diary, and share the printouts with your doctor at each visit.

Get a helping hand during your Lupron Depot therapy. Sign up for ScriptAssist, a free program that offers personalized support from registered nurses.

Important Safety and Other Information:

Lupron Depot^® is indicated for management of endometriosis, including pain relief and reduction of endometriotic lesions. Lupron Depot with norethindrone acetate 5 mg daily is also indicated for initial management of endometriosis and for management of recurrence of symptoms. Duration of initial treatment or retreatment should be limited to 6 months.

Most common side effects with Lupron Depot are generally those related to low estrogen levels, including hot flashes, headaches, and vaginal dryness. A small amount of bone loss (average 3.2% at month 6) may also occur during therapy with Lupron Depot alone.

The most commonly reported side effects of Lupron Depot plus norethindrone acetate 5 mg daily are hot flashes, headache, nausea/vomiting, depression/emotional liability, and asthenia. In addition, Lupron Depot plus norethindrone acetate-treated patients had significantly decreased HDL levels and significantly increased LDL/HDL rations. After treatment, mean serum lipid levels in patients with follow-up data returned to pretreatment values. Norethindrone acetate should be used with caution in women with cardiovascular risk factors including lipid abnormalities and cigarette smoking. Please refer to the norethindrone acetate prescribing information for warnings, precautions, contraindications, and adverse reactions.

Please see Complete Prescribing Information, as well as the Patient Product Information for Lupron Depot.

Visit www.lupron.com